Seroprevalence of Toxoplasma gondii Immunoglobulin G and Immunoglobulin M Antibodies among Leukemia Patients in Erbil City-Kurdistan Region/Iraq by Enzyme-linked Immunosorbent Assay Technique

Hemdad H. Mawlood, Department of Medical Lab Technology, Erbil Technical Health and Medical College, Erbil Polytechnic University, Erbil, Kurdistan Region, Iraq, 2Department of Medical Laboratory Science, College of Science, Knowledge University, Erbil, Kurdistan Region, Iraq Follow

Corresponding Author

Hemdad H. Mawlood

Authors ORCID

0000-0001-5810-7722

Document Type

Research Article

Abstract

The current study was revealed the seroprevalence of Toxoplasma gondii immunoglobulin (Ig)G and IgM among different types of leukemia (Acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin lymphoma [HL], multiple myeloma [MM], non-HL [NHL], and chronic myeloid leukemia) from male and female patients in different age groups (18–≥48 years) using indirect enzyme-linked immunosorbent assay. The results of 140 cases of different types of leukemia showed the highest T. gondii IgG (44.44%) among MM leukemia whereas T. gondii IgM highest (12.5%) among NHL leukemia. Significant (P ≤ 0.01) differences between T. gondii antibodies and age group were recorded, that increased with the age of Leukemia patients. Hence, it could be concluded that multiple myeloid leukemia is strong immunocompromised and high significant (P ≤ 0.01) with toxoplasmosis.

Keywords

Enzyme-linked immunosorbent assay, Immunoglobulin G, Immunoglobulin M, Leukemia, Toxoplasma gondii

How to Cite This Article

Mawlood, Hemdad H. (2021) "Seroprevalence of Toxoplasma gondii Immunoglobulin G and Immunoglobulin M Antibodies among Leukemia Patients in Erbil City-Kurdistan Region/Iraq by Enzyme-linked Immunosorbent Assay Technique," Polytechnic Journal: Vol. 11: Iss. 2, Article 1.
DOI: https://doi.org/10.25156/ptj.v11n2y2021.pp1-6