The Dissolution enhancement of Meloxicam tablets from the synergistic effect of hydrotropic and sublimating agent

Authors

Hemn L. Qader, Department of pharmaceutics, College of pharmacy, Hawler Medical University, Kurdistan Region, Iraq
Tara A. Abdula, Hawler Medical UniversityFollow
Huner K. Omer, Hawler Medical UniversityFollow

How to Cite This Article

Qader, Hemn L.; Abdula, Tara A.; and Omer, Huner K. (2021) "The Dissolution enhancement of Meloxicam tablets from the synergistic effect of hydrotropic and sublimating agent," Polytechnic Journal: Vol. 11: Iss. 2, Article 16.
DOI: https://doi.org/10.25156/ptj.v11n2y2021.pp100-108

Document Type

Original Article

Abstract

Background and Objective: Drugs which fall into Class II of Biopharmaceutical Classification System suffer from poor aqueous solubility that limits the dissolution and oral bioavailability. The improvement of the dissolution rate of this class of drug is an important issue for enhancing their bioavailability and therapeutic efficacy. The objective of this study is to investigate the magnitude of enhancement of the dissolution rate of Class II drug “Meloxicam (MLX)” by using more than one solubility enhancement technique.

Publication Date

12-30-2021

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